The UCLA Depression Grand Challenge (DGC) has come a long way since it’s initial annoucement last October 2015. The initiative is tackling depression in an unprecedented manner with an aim to better understand and treat this devastating disease. One year later, the DGC has begun a series of studies and set a program in place that will screen and treat UCLA student and staff for depression. At the heart of the UCLA initiative, is the 10-year “100K Study” that will monitor 100,000 people with the goals of identifying the genetic and environmental causes of depression. The study is the largest of its kind to date and will screen for depression by examining participants’ genetics and assessing symptoms through remote monitoring.
At the center of the Depression Grand Challenge (DGC) is a 10-year “100K Study,” in which researchers will monitor 100,000 people with the aim of identifying the genetic and environmental causes of depression.
The 100K Study will screen for depression, analyze participants’ genetics, measure early adversity and life stress and assess symptoms through remote monitoring using cell phones and wearable devices. In preparation for each of the facets of the 100K Study, demonstration projects are underway. Each demonstration study involves human participants. Explore the Guide to human studies demonstration projects to learn more about current and anticipated studies.
The Depression Grand Challenge is tackling depression in an unprecedented manner and most notably sets itself apart by following a unique multidisciplinary and large-scale approach. Dr. Jonathan Flint, author of the largest genetics study to date, joined the UCLA Depression Grand Challenge team earlier this year. Dr. Flint is one of four directors of the study and notes the study’s novel approaches to funding that may potentially utilize a stakeholder science where participants pay to enroll in a study. With this method, both participants and researchers will benefit from the genetic sequencing employed in the study.
Read more at David Geffen School of Medicine
UCLA Depression Grand Challenge is teaming up with UCLA’s Code for the Mission to develop a dynamic and scalable mobile app for tracking an individual’s prescription medication usage and psychotherapies. The deadline for Team Registration is Friday, June 17.
The winning team will receive $5,000 and contribute to the field of medical health research! If you are interested in learning more, please visit the Code for Mission website here.