Examples of gene networks in the hippocampus affected by brain trauma. UCLA researchers report that the “master regulator” genes (in red) influence many other genes responsible for the effects of brain trauma.
UCLA researchers are the first to identify master genes that may control hundreds of genes linked to diseases such as depression, Alzheimer’s and many more. Traumatic brain injury (TBI) seems to damage these master genes, which then alters gene expression and/or protein production of genes linked to the master gene. Using an animal model, researchers simulated TBI among a cohort of rats and drew RNA from the rats. Among rats with simulated Read more →