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Depression

UCLA’s Jonathan Flint debunks theory of “warrior gene” but signals possibility of predicting behavioral outcomes based on genetics

Jonathan Flint (UCLA behavioral geneticist, expert in the genetic determinants of depression and Depression Grand Challenge Executive Committee team member) shared background about the theory of the “warrior gene” in a blog post written for the Oxford University Press. Since the 1990s criminal defense lawyers have tried to argue that a mutation in the “warrior gene” mitigates responsibility for aggressive behavior. Flint highlights a 2021 New Mexico Supreme Court case which definitively ended the argument that a single gene mutation determines overall behavior.

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Depression

Study led by Michael Fanselow at UCLA proposes connection between brain injuries and the onset of anxiety disorders

Michael Fanselow, distinguished professor of psychology (UCLA Life Sciences) and psychiatry & biobehavioral sciences (David Geffen School of Medicine), led a study focusing on the connection between traumatic brain injuries and anxiety disorders, such as post-traumatic stress disorder (PTSD). The study was published in Scientific Reports, a sub journal of Nature.

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Depression

Katherine Narr discusses effects of ketamine versus ECT when treating refractory depression

In a recent press release by MDedge Psychiatry – an online journalism resource – Katherine Narr, associate professor of neurology and psychiatry and biobehavioral sciences at the David Geffen School of Medicine, discussed the results from a study performed as part of the Depression Grand Challenge’s Serial Ketamine Infusion Biomarkers demonstration project.

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Depression

UCLA study reveals new info about what is happening with brain cells in people with autism

Daniel Geschwind, professor of Neurology and Psychiatry at David Geffen School of Medicine at UCLA, and Xinshu (Grace) Xiao, UCLA’s Maria R. Ross professor of integrative biology and physiology, published research results revealing new clues about differences in the brain cells between people with autism and a control group. The focus of the study was RNA editing. Although difficult to know if it is causation or a result, the study found that people with autism had reduced editing.

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