Archive Tag: Structure

Depression Grand Challenge Worldwide Passes Initial Screening

Today, we learned that the DGC Worldwide application to the MacArthur Foundation’s 100&Change competition passed the initial screening round. The field has narrowed from 1,900 to 800 applications. MacArthur Foundation is expected to name 10 semifinalists by the end of January, one of which will eventually receive a $100M award.

Read more about the DGC Worldwide and view the DGC Worldwide 100&Change video.

Through the initiative, UCLA experts are identifying specific mechanisms that put people at risk for depression and creating customized suites of treatments for each patient.
UCLA Health

The UCLA Depression Grand Challenge (DGC) has come a long way since it’s initial annoucement last October 2015. The initiative is tackling depression in an unprecedented manner with an aim to better understand and treat this devastating disease. One year later, the DGC has begun a series of studies and set a program in place that will screen and treat UCLA student and staff for depression. At the heart of the UCLA initiative, is the 10-year “100K Study” that will monitor 100,000 people with the goals of identifying the genetic and environmental causes of depression. The study is the largest of its kind to date and will screen for depression by examining participants’ genetics and assessing symptoms through remote monitoring.

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An overview of the Depression Grand Challenge human studies demonstration projects that are underway

At the center of the Depression Grand Challenge (DGC) is a 10-year “100K Study,” in which researchers will monitor 100,000 people with the aim of identifying the genetic and environmental causes of depression.

The 100K Study will screen for depression, analyze participants’ genetics, measure early adversity and life stress and assess symptoms through remote monitoring using cell phones and wearable devices. In preparation for each of the facets of the 100K Study, demonstration projects are underway. Each demonstration study involves human participants. Explore the Guide to human studies demonstration projects to learn more about current and anticipated studies.

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Depression Grand Challenge Worldwide Application Submitted to MacArthur Foundation 100&Change

What would happen if our greatest shared burden were lifted? That’s the vision for Depression Grand Challenge Worldwide. The UCLA Depression Grand Challenge team has partnered with collaborators around the globe to create a solution that provides underserved populations with state-of the-art treatment for depression. The expanded team submitted a proposal to the MacArthur Foundation’s groundbreaking 100&Change competition by the October 3, 2016 deadline. The proposed approach utilizes smartphones and the internet to offer an integrated treatment and technology solution to diagnose, treat and continuously monitor individuals with depression from underserved populations. And importantly the techniques and strategies are customized for each treatment site, taking into account life and cultural experiences.  Keep your fingers crossed that we have a chance to take the DGC Worldwide.

View the DGC Worldwide 100&Change video.

City of Los Angeles' Chief Sustainability Officer, Matt Petersen, (right) addressing the room.
City of Los Angeles’ Chief Sustainability Officer, Matt Petersen, (right) addressing the room.
Nikki Parrish

On September 22nd, the Sustainable LA Grand Challenge held its inaugural Leadership Council meeting, which brought together leadership from across disciplines at UCLA and throughout Los Angeles County. Headlined by Chancellor Gene Block and Mark Gold, Associate Vice Chancellor for Environment and Sustainability, the meeting focused on laying the foundation for the Council to help move Sustainable LA to the next level. Among many of the responsibilities, the Sustainable LA Grand Challenge Leadership Council will provide implementation expertise, identify pathways to research, as well as grow and strengthen the Council.

California Senator Kevin de León, a member of the Leadership Council, commended Chancellor Block and the university for the innovative and forward thought put into this Grand Challenge. In a statement at the meeting Senator de León emphasized,

“California will lead, and is working to set a market signal to build the technologies and meet the goals of the targets that it has set. We have the capital, and we have the opportunity to lead the world. We have to get it right here.”

UCLA is not only the key to this interdisciplinary and innovative approach to research, it’s also positioned to help effect societal change.